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You have accessJournal of UrologyPediatrics III (MP50)1 May 2024MP50-17 OPTIMAL FREQUENCY USED IN TRANSCUTANEOUS ELECTRIC NERVE STIMULATION (TENS) FOR TREATING NOCTURNAL ENURESIS IN CHILDREN Andrew Rosenzweig, Brian Meyerson, Alexandra Rehfuss, and Adam S. Howe Andrew RosenzweigAndrew Rosenzweig , Brian MeyersonBrian Meyerson , Alexandra RehfussAlexandra Rehfuss , and Adam S. HoweAdam S. Howe View All Author Informationhttps://doi.org/10.1097/01.JU.0001008684.57262.97.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Transcutaneous electric nerve stimulation (TENS) has been studied previously for monosymptomatic nocturnal enuresis (NE) with the best outcomes seen in when placing the TENS pad along the posterior tibial nerve. Marshall Stoller had previously studied different frequencies used for posterior tibial nerve stimulation in monkeys over 25 years ago, but there has not been any investigation into this since, and there have been no studies looking at different frequencies when using TENS for voiding conditions. In this study, we aim to identify the optimal frequency in TENS therapy for NE. METHODS: A randomized clinical trial including 89 patients aged 5-18 years presenting with monosymptomatic NE was performed. After one month of behavioral therapy, they were treated with TENS therapy in the posterior tibial location after randomization to one of three frequency settings on the TENS unit: 2, 10, and 150 Hz. TENS therapy was performed nightly at home for 15 minutes before bed for one month. Voiding diaries recording the number of wet nights, wet scale severity score (0-3), TENS compliance, quality of life (QOL) questionnaires (PIN-Q), and any adverse reactions were collected after baseline and after TENS therapy. RESULTS: Only one patient (in the 10Hz frequency group) was completely cured of NE after one month of TENS therapy. The 150 Hz frequency TENS setting showed the greatest decrease in the rate of wet nights (11.1%) compared to other groups (9.9% for 10 Hz and 10.5% for 2 Hz). The 2 Hz frequency showed the greatest decrease in mean wet scale severity score (-0.42) compared to other groups (-0.15 for 10 Hz and -0.19 for 150 Hz). The 150 Hz frequency group showed the greatest improvements in quality of life with PIN-Q score improving by 2.54 points (compared to 10 Hz with improvement of 0.70 points, and the 2 Hz group actually showed no improvement with a 0 point change). Compliance rates with TENS were excellent for all groups (94%, 91%, and 87% for 2 Hz, 10 Hz, and 150 Hz, respectively). These results were not statistically significant. There were no adverse events with TENS therapy. 81%, 73%, and 87% of the patients in the 2 Hz, 10 Hz, and 150 Hz groups, respectively, said they would use TENS therapy again for NE. CONCLUSIONS: TENS therapy when combined with behavioral modifications can be an easy and safe tool used at home to help with treating NE in children. Lower frequencies seem to be optimal for this type of treatment. Further studies are needed to optimize this therapy to show a clinically significant benefit. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e838 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Andrew Rosenzweig More articles by this author Brian Meyerson More articles by this author Alexandra Rehfuss More articles by this author Adam S. Howe More articles by this author Expand All Advertisement PDF downloadLoading ...
Rosenzweig et al. (Mon,) studied this question.
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