Pd49-01 Long-Term Outcome of Gender Reassignment in 46xy DSD Patients in Multicultural Society

You have accessJournal of UrologyPediatrics V (PD49)1 May 2024PD49-01 LONG-TERM OUTCOME OF GENDER REASSIGNMENT IN 46XY DSD PATIENTS IN MULTICULTURAL SOCIETY Binyamin B. Neeman, Jawdat Jaber, Stanislav Kocherov, Floris Levy-Khademi, Amicur Farkas, and Boris Chertin Binyamin B. NeemanBinyamin B. Neeman , Jawdat JaberJawdat Jaber , Stanislav KocherovStanislav Kocherov , Floris Levy-KhademiFloris Levy-Khademi , Amicur FarkasAmicur Farkas , and Boris ChertinBoris Chertin View All Author Informationhttps://doi.org/10.1097/01.JU.0001008752.72292.d7.01AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The decision regarding sex rearing in patients with Disorders of Sex Development (DSD) is heavily connected to the shared decision-making model within multidisciplinary team. Some of these patients might develop gender identity disorder (GID), when they become adults. We have aimed to evaluate the long-term outcomes of patients with XY DSD who underwent female gender reassignment at our center. METHODS: We have conducted a retrospective study of all 46 XY DSD patients who underwent female reassignment in our institution over the last 30 years. RESULTS: We have identified 25 patients who have matched study criteria. Of those, 8(32%) with primary diagnosis of 3 β-hydroxysteroid dehydrogenase deficiency, 10(40%) with partial or complete androgen insensitivity syndrome, 1(4%) with 5α-reductase deficiency, 3(12%) with Ovotestis DSD and Mixed gonadal dysgenesis in the remaining 3(12%) patients. 13(52%) patients were Jewish, 6(24%) Muslims and the remaining 6(24%) were Christians. The decision on gender rearing was made by the parents in 15(60%), by the patient in 7(28%), and in the remaining 3(12%) by the surgical team during hernia repair.14(56%) out of 25 patients agreed to answer questionnaires regarding sexual function and satisfaction from gender assignment. 2 patients regretted the decision of female gender assignment. The first with 5α-reductase deficiency, who made the decision for reassignment herself as an adult and the other (3β-hydroxysteroid dehydrogenase) who underwent gonadectomy during inguinal exploration as a child. The rest of the patients were satisfied with the choice of gender, 3 need psychological support on the daily basis. 5 have sex on a regular basis (four satisfied, one suffers from pain in the groin) The overall FSFI score was 28.8±5 which included the scores 3.8, 4.2, 4.2, 4.2, 3.8 in the categories desire, arousal, lubrication, orgasm, satisfaction, and pain respectively. In the study group, relationship and cohabitation were significantly later in life compared to the general population. CONCLUSIONS: Despite the sensitivity of the subject and cultural differences, most patients were satisfied with the decision to undergo female gender reassignment. Over the years, patients require meticulous follow-up in order to consider additional interventions, and mental support if it is necessary. The two cases of later regret highlight the importance of proper education of patients, their families and medical providers upon decision on gender assignment. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1050 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Binyamin B. Neeman More articles by this author Jawdat Jaber More articles by this author Stanislav Kocherov More articles by this author Floris Levy-Khademi More articles by this author Amicur Farkas More articles by this author Boris Chertin More articles by this author Expand All Advertisement PDF downloadLoading ...