Review on the Toxicity and Safety of Medicinal Plants during Pregnancy

firstₚage Download PDF settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessAbstract Review on the Toxicity and Safety of Medicinal Plants during Pregnancy † by Aniket Rajesing GiraseAniket Rajesing Girase SciProfiles Scilit Preprints. org Google Scholar 1, *, Javesh Kashinath PatilJavesh Kashinath Patil SciProfiles Scilit Preprints. org Google Scholar 1, Devshree Yashwantbhai PatelDevshree Yashwantbhai Patel SciProfiles Scilit Preprints. org Google Scholar 1, Harsha Vasudev ChaudhariHarsha Vasudev Chaudhari SciProfiles Scilit Preprints. org Google Scholar 1 and Sachinkumar Madhukar MahajanSachinkumar Madhukar Mahajan SciProfiles Scilit Preprints. org Google Scholar 2 1 Department of Pharmaceutical Quality Assurance, P. S. G. V. P. Mandal's College of Pharmacy, Shahada 425409, Maharashtra, India 2 KVPS's Institute of Pharmaceutical Education, Boradi, Tal-Shirpur 425405, Maharashtra, India * Author to whom correspondence should be addressed. † Presented at the 1st International Electronic Conference on Toxics, 20–22 March 2024; Available online: https: //sciforum. net/event/IECTO2024. Proceedings 2024, 102 (1), 40; https: //doi. org/10. 3390/proceedings2024102040 Published: 3 April 2024 Download keyboardₐrrowdown Download PDF Download PDF with Cover Download XML Download Epub Versions Notes Keywords: toxicology; toxic plants; safety; pregnancy; teratogens Introduction: Although herbs are widely used and considered safe, they can be toxic, especially during pregnancy. Most reports of toxic plants are the result of misidentification of the plants in sales records or improper preparation and handling by untrained staff. Therefore, these plants are best managed by experienced staff. Medicinal plant uses can be particularly advantageous to low-income patients, as drug treatment is expensive. It is important for doctors to understand the composition, benefits, and potential toxic effects of the herbs that they dispense and prescribe and to provide preventive and safe treatment. Pregnant women will continue to be a major target for teratological screening for at least the next few years. Method: Toxicology testing includes pharmacological safety, immunotoxicity and antigenicity, endocrine toxicity, gastrointestinal toxicity, enterotoxicity, nephrotoxicity, hepatotoxicity, and drug studies. Phytochemicals and their metabolites are known to cause uterine contractions and hormonal imbalances, leading to miscarriage. Conclusions: Advances in new technologies have revolutionized our understanding of biology and may facilitate decisions regarding the identification of teratogens. Serious illnesses during pregnancy pose exceptional challenges to healthcare providers because they have the potential to harm the mother and fetus. Teratogenic effects from poisons or antibiotics can be life-threatening. Plants such as acacia, ailanthus, aloe vera, aristolochia, areca nut, bamboo, cassia, ragweed, lemongrass, and racemic black cohosh should be avoided during pregnancy. Result: A recent international study found that only 22% of medicinal plants used by pregnant women were safe to use during pregnancy. Similarly, a study conducted in Asia found that only 39% of the most commonly used medicinal plants by pregnant women were safe to use during pregnancy. Author ContributionsConceptualization, A. R. G. and J. K. P. ; methodology, J. K. P. and D. Y. P. ; data collection, D. Y. P. and H. V. C. ; analysis, J. K. P. and S. M. M. ; writing—original draft, A. R. G. ; writing—review supervision, J. K. P. All authors have read and agreed to the published version of the manuscript. FundingThis research received no external funding. Institutional Review Board StatementNot applicable. Informed Consent StatementNot applicable. Data Availability StatementData sharing is not applicable to this abstract. Conflicts of InterestThe authors declare no conflicts of interest. Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author (s) and contributor (s) and not of MDPI and/or the editor (s). MDPI and/or the editor (s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https: //creativecommons. org/licenses/by/4. 0/). Share and Cite MDPI and ACS Style Girase, A. R. ; Patil, J. K. ; Patel, D. Y. ; Chaudhari, H. V. ; Mahajan, S. M. Review on the Toxicity and Safety of Medicinal Plants during Pregnancy. Proceedings 2024, 102, 40. https: //doi. org/10. 3390/proceedings2024102040 AMA Style Girase AR, Patil JK, Patel DY, Chaudhari HV, Mahajan SM. Review on the Toxicity and Safety of Medicinal Plants during Pregnancy. Proceedings. 2024; 102 (1): 40. https: //doi. org/10. 3390/proceedings2024102040 Chicago/Turabian Style Girase, Aniket Rajesing, Javesh Kashinath Patil, Devshree Yashwantbhai Patel, Harsha Vasudev Chaudhari, and Sachinkumar Madhukar Mahajan. 2024. "Review on the Toxicity and Safety of Medicinal Plants during Pregnancy" Proceedings 102, no. 1: 40. https: //doi. org/10. 3390/proceedings2024102040 Article Metrics No No Article Access Statistics Multiple requests from the same IP address are counted as one view.