WCN24-2097 Real life lupus nephritis: long-term prognostic value of proteinuria outside of a trial

Current recommendations for the treatment of lupus nephritis (LN) suggest a goal-oriented treatment aimed at achieving the optimization of renal function and a proteinuria/creatininuria ratio between 500-700 mg/g at 12 months (complete clinical response). This level of proteinuria was found to have the greatest ability to predict a good long-term renal outcome in randomized clinical trials. The main objective of this study was to assess the long-term prognostic value of proteinuria after the first year of treatment in patients with LN, in a real-life retrospective cohort.