Measuring the Health Co-Benefits of Air Pollution Interventions on Premature Deaths in Canadian Cities

Background: Climate change has significant consequences on human health. Cities are especially vulnerable, where air pollution is a major environmental health risk. Premature mortality (i.e., deaths before age 75) is a robust population health outcome amenable to targeted policy and programmatic interventions. We used the Premature Mortality Population Risk Tool augmented with environmental data (PreMPoRT-ENV) to predict the 5-year incidence of premature deaths under air pollution reduction policies. Methods: PreMPoRT-ENV is a sex-specific Weibull accelerated failure time survival model that uses the Canadian Community Health Survey (CCHS) linked to the Canadian Vital Statistics Death Database and environmental data. We applied PreMPoRT-ENV to the 2016–2017 CCHS cycles and simulated Canadian Ambient Air Quality Standards targets to predict their impact on premature mortality across Canadian census metropolitan areas. We simulated capping annual mean particulate matter 2.5 microns or less in diameter (PM 2.5 ) and nitrogen dioxide (NO 2 ), as well as reducing air pollutants by 10% and 25% plus capping. Results: The weighted sample included 9,240,000 females and 9,260,000 males. Capping PM 2.5 to 8.8 μg/m 3 and NO 2 to 12.0 ppb resulted in 12 per 100,000 fewer predicted premature deaths than observed exposures over 5 years (1,110 fewer absolute premature deaths). Reducing air pollutants by 10% and 25% plus capping resulted in even fewer predicted premature deaths. Conclusion: Our study highlights how to use a model that predicts premature mortality to provide estimates of the health impacts of environmental vulnerabilities. Results suggest that more aggressive targets may be needed to further realize population health benefits.