Isolation and Antibiotic Susceptibility of Escherichia coli from Urinary Tract Infections

Background and Objective: Escherichia coli is the most prevalent bacteriological agent responsible for Urinary Tract Infections (UTIs) in humans, as well as the most common nosocomial infection in developed countries.The broad availability of antimicrobial drugs has made them difficult to treat due to the emergence of infections with rising antibiotic resistance.The study was carried out in a tertiary care hospital in Sirajganj on a urinary tract infection with Escherichia coli for isolation and diagnosis of antibiotic resistance.Materials and Methods: Urine samples (n = 296) were obtained from patients exhibiting signs and symptoms of urinary tract infections.Bacteria were extracted and identified using conventional biochemical techniques.The Kirby-Bauer method was used to determine E. coli resistance to various antibiotics.Results: A bacterial etiological agent was recovered from 79 samples, with E. coli having he ighest revalence 54, 8.4%), ollowed y taphylococcus ureus 12.6%), Pseudomonas species (10.1%) and Klebsiella species (8.9%).The Escherichia coli was highly resistant to Ceftazidime (85.2%),Ceftriaxone (72.2%),Amoxycillin (68.5%) and Nalidixic acid (64.8%), followed by intermediate resistance to Cefuroxime (59.3%),Netilmicin (51.9%),Azithromycin (50.0%) and Ciprofloxacin (40.7%) and low resistance to Gentamycin (31.5%),Nitrofurantoin (27.8%) and Imipenem (13.0%).Out of 79 Escherichia coli isolates, 60 (75.9%) were declared as multiple drug-resistant and 2 (2.5%) were extensive drug-resistant.Conclusion: It has been determined that multiple medication-resistant Escherichia coli is to blame for the majority of human urinary tract infections.