Endoscopic 5-Aminolevulinic Acid–Induced Fluorescence-Guided Intraparenchymal Brain Tumor Resection—Can the Endoscope Detect More Fluorescence Than the Microscope?

Using a laboratory-based optical setup, we show that 5-aminolevulinic acid (5ALA) fluorescence is better detected using the endoscope than the microscope. Furthermore, we present our case series of fully endoscopic 5ALA-guided resection of intraparenchymal tumors.