Ionic liquid‐supported copper‐catalyzed synthesis of 2H‐indazoles under microwave irradiation

Abstract Five‐membered indazoles are recognized as a special scaffold having a broad spectrum of pharmacological properties among other heterocyclic compounds. New methods must be developed for the effective synthesis of 2 H ‐indazole because of the exceptionally high biological activity of compounds containing a 2 H ‐indazole core. We present the ionic liquid‐supported copper‐catalyzed one‐pot synthesis of 2 H ‐indazoles under microwave irradiation, continuing our ongoing investigation of the potential uses of bioactive compounds produced in the lab. The use of microwave and ionic liquid‐supported catalyst makes this process greener and more highly energy efficient than the conventional reported methods. Overall, by forming consecutive C‐N and N‐N bonds with the help of an ionic liquid‐supported copper catalyst, we have developed a novel green one‐pot technique for the synthesis of the 2 H ‐indazole motifs in very high yield.