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Figure S2. Correlations between IGR burden, TMB and Indels in the ICGC Pan-cancer dataset. (a) Scatter plot of Indel burden (x-axis) and TMB (y-axis), colored by T-inflamed signature. (b) Scatter plot of Indel burden (x-axis) and IGR burden (y-axis). (c) Median Indel burden vs tumor mutation burden for each cancer type. (d) Median Indel burden vs IGR burden for each cancer type. Dotted lines in (c, d) indicate mean plus one standard deviation cutoffs of the corresponding biomarkers.
Zhang et al. (Mon,) studied this question.