February 26, 2024Open Access

A novel model to study mechanisms of cholestasis in human cholangiocytes reveals a role for the SIPR2 pathway

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

Ductular reactivity is central to the pathophysiology of cholangiopathies. Mechanisms underlying the reactive phenotype activation by exogenous inflammatory mediators and bile acids are poorly understood.

Leer artículo completoexternamente

Me gusta

Guardar

Ver artículo completo

Cite This Study

Islam et al. (Mon,) studied this question.

synapsesocial.com/papers/68e778cdb6db6435876ed107 https://doi.org/https://doi.org/10.1097/hc9.0000000000000389

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1ImageJ2: ImageJ for the next generation of scientific image data2017 · 6,252 citations
2A New Xenobiotic-Induced Mouse Model of Sclerosing Cholangitis and Biliary Fibrosis2007 · 378 citations
3Increased susceptibility of cholangiocytes to tumor necrosis factor-α cytotoxicity after bile duct ligation2003 · 54 citations
4Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids2017 · 294 citations
5Combinatorial allosteric modulation of agonist response in a self-interacting G-protein coupled receptor2020 · 10 citations

Me gusta

Guardar

Ver artículo completo