Treatment Temperature and Magnetic Field Distribution for Magnetic Hyperthermia Using Magnetic Nanoparticles

A minimally invasive cancer treatment method utilizing magnetic nanoparticles (MNPs) and magnetic coils, magnetic hyperthermia, generates heat locally inside the body to degenerate cancer cells. The uniformity of the coil's magnetic field is a crucial factor in enhancing the therapeutic effect. In this study, we evaluated the temperature distribution of MNPs on induction heating experiments at various distances using two types of coils. We found that the 2‐turn coil with a larger outer diameter and higher magnetic field uniformity resulted in a treatment temperature region approximately twice as wide as the 4‐turn coil, indicating the enhancement of the treatment effect under the uniform magnetic field distributions. © 2024 Institute of Electrical Engineer of Japan and Wiley Periodicals LLC.