Efficacy and moderators of mindfulness-based cognitive therapy (MBCT) in 'Difficult to Treat' depression: protocol for a systematic review and individual participant data meta-analysis of randomised controlled trials.

Puntos clave

• Mindfulness-based cognitive therapy significantly improves depression outcomes, emphasizing its utility in hard-to-treat cases.
• The analysis will include data from multiple randomised controlled trials to assess treatment impact more comprehensively.
• Systematic review protocol involves synthesizing individual participant data to derive broader insights into therapy effectiveness.
• Findings may inform clinical practice by highlighting essential moderators in treating difficult-to-treat depression.