What question did this study set out to answer?

This report aims to detail a case of granular cell variant leptomeningeal gliomatosis and its molecular characterization.

January 23, 2026

A Granular Cell Variant of Adult Primary Leptomeningeal Gliomatosis Mimicking a Granulomatous Process: A Case Report With Molecular Characterization

Puntos clave

This report aims to detail a case of granular cell variant leptomeningeal gliomatosis and its molecular characterization.
Clinical assessment of a 77-year-old patient
Radiological imaging to identify tumor characteristics
Molecular studies conducted for diagnosis confirmation
Post-mortem examination to analyze tumor details
Granular cell morphology was observed in biopsy
Initial misdiagnosis as a granulomatous process
Comprehensive molecular studies revealed IDH-wildtype glioblastoma

Resumen

ABSTRACT We report the case of a 77‐year‐old patient with glioblastoma, IDH‐wildtype, presenting as adult primary leptomeningeal gliomatosis with granular cell morphology in the biopsy. The clinico‐radiological presentation initially suggested a non‐neoplastic granulomatous process. Comprehensive molecular studies and post‐mortem examination were subsequently performed.

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Cite This Study

Brito et al. (Tue,) studied this question.

synapsesocial.com/papers/69730f34c8125b09b0d1ef7f https://doi.org/https://doi.org/10.1111/neup.70041

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