What question did this study set out to answer?

The aim was to evaluate the outcomes of the SADI-S procedure over six years in a single center.

January 25, 2026

IBC Oxford Oral Abstract 21 - Single anastomosis duodeno-ileal (SADI) procedure outcomes: 6 years’ experience

Puntos clave

The aim was to evaluate the outcomes of the SADI-S procedure over six years in a single center.
Retrospective data collection from patients who underwent SADI from June 2018 to October 2024
Included primary, staged, and conversional cases post other bariatric procedures
Analyzed BMI, total body weight loss, GERD-HRQL scores, and resolution of obesity-related diseases
Significant weight reduction with BMI decreasing from 53.4 to 33.4 kg/m2
Complete resolution of type II diabetes in three patients
Hypertension resolved in two patients, with one on minimal medication
Improvement in hemoglobin levels for 29.6% of patients
67% decrease in GERD-HRQL scores post-surgery with no procedure-related mortality

Resumen

Abstract Introduction The SADI procedure represents one of the recent approaches to metabolic and bariatric surgery, which provides excellent weight reduction and improvement of obesity related diseases. The purpose of this study was to evaluate the 6-year outcomes of the SADI-S procedure in a single center. Methods Data were collected retrospectively for patients who underwent SADI from June 2018 to October 2024, including primary (one-stage), staged, and conversional cases after prior metabolic and bariatric procedures (sleeve gastrectomy, gastric band, or vertical banded gastroplasty) or gastric balloon. The data included in this study were the BMI Pre and Post SADI, total body weight loss (TBWL), excess weight loss (EWL), gastrointestinal reflux effect with GERD-Health Related Quality of Life Questionnaire (GERD-HRQL) score assessment, nutritional status, improvement or resolution of obesity related diseases, and perioperative adverse events. Results A total of 27 (18 female, 9 male) patients were operated. The patients showed successful weight reduction (BMI 53.4 ± 10.6 kg/m2 to BMI 33.4 ± 6.9 kg/m2, P 0.0000). Three patients with diabetes type II had complete resolution (pre op HgA1c 7.1 ± 0.71%, post op HgA1c 5.1 ± 0.53%). Hypertension was resolved in two patients, and one patient required a single antihypertensive agent. Complete resolution of obstructive sleep apnea was observed in both patients (7.1%). Although four patients developed iron deficiency anemia in 4/27 (14.8%), 8patients (29.6%) showed improvement of hemoglobin levels (1 g/dL). Hypoalbuminemia occurred in 3 patients (11.1%). GERD-HRQL decreased by ∼67% postoperatively (pre op GERD-HRQL 13.8 ± 16.8, post op GERD-HRQL 4.6 ± 6.4, P = 0.02). There was zero procedure related mortality, reoperation or readmission. Conclusion The SADI is a safe and highly effective procedure for patients with extreme obesity in well-selected and compliant patients. Continuous monitoring and supplementation are required to prevent malnutrition. Long- term follow up is essential to assess the effects on cardiovascular outcomes, cancer risk, and obesity-related mortality.

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Cite This Study

Alayed et al. (Thu,) studied this question.

synapsesocial.com/papers/6975b2eafeba4585c2d6e570 https://doi.org/https://doi.org/10.1093/bjs/znaf288.021

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