ABSTRACT Exposure and response prevention (ERP) remains the gold‐standard psychotherapy for obsessive–compulsive disorder (OCD), yet real‐world care is limited by dropout, partial response, relapse, and phenotypes that strain habituation‐centric protocols. This commentary synthesizes five case reports that upgrade ERP not by replacing it, but by refining how inhibitory learning is taught and enacted. In the first case study by ref, Acceptance and Commitment Therapy (ACT) with values‐based exposure shifted the goal from distress reduction to values‐consistent action under aversive private events, boosting motivation and generalization. In the second case (ref), VR‐assisted avatar therapy externalized the OCD voice”, boosting insight and resistance to compulsions and thereby unlocking ERP. In the third case (ref), addressing mental contamination, imagery rescripting reframed shame and disgust. In the fourth case (ref), ERP was tuned to emphasize clear expectancy violations and to vary contexts. In the fifth and final case study by ref., the focus was on “innovative moments” during ERP. Noticing and amplifying these small, natural shifts (“exceptions”) kept the client engaged and helped solidify new response patterns. Together, these vectors suggest a next wave of OCD care: precise personalization of ERP's mechanism (expectancy violation/inhibitory learning), process targets (motivation, insight, psychological flexibility and non‐fear emotions like shame and disgust), and format (tech‐assisted delivery), evaluated with mechanism‐linked outcomes. Rather than “more ERP,” the field should engineer better operating conditions for ERP—one explicit prediction, one values‐anchored action, and one reinforced micro‐gain at a time.
Jakob Fink‐Lamotte (Thu,) studied this question.