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February 2, 2026
Open Access
Lactoferrin reduces febrile neutropenia in children receiving chemotherapy for hematologic malignancies: a randomized, placebo-controlled trial
PL
Paola Lago
AULSS 2 Marca Trevigiana
DZ
Daniele Zama
EM
Edoardo Muratore
Azienda USL di Bologna
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Puntos clave
To assess the effectiveness of lactoferrin in reducing febrile neutropenia in children undergoing chemotherapy for hematologic malignancies.
Randomized, placebo-controlled trial
Inclusion of children with hematologic malignancies
Administration of lactoferrin vs. placebo during chemotherapy
Significantly reduced episodes of febrile neutropenia in the lactoferrin group
Improved overall treatment tolerance observed
No significant adverse effects reported related to lactoferrin use
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Cite This Study
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Lago et al. (Thu,) studied this question.
synapsesocial.com/papers/6980fbf6c1c9540dea80dcee
https://doi.org/https://doi.org/10.3324/haematol.2025.300007
Lactoferrin reduces febrile neutropenia in children receiving chemotherapy for hematologic malignancies: a randomized, placebo-controlled trial | Synapse