Drug induced bilateral acute angle closure is an ophthalmic emergency that can lead to vision threatening sequelae if not recognized and treated promptly. Acetazolamide is a Sulphonamide derivative implicated in this peculiar phenomenon. Acute bilateral angle closure happens due to an idiosyncratic mechanism. This drug is widely employed in various specialties apart from Ophthalmology. We report a case of bilateral acute angle closure crisis following administration of oral Acetazolamide after a retinal detachment surgery. Though this is a well-recognized side effect, the diagnosis was challenging due to the confounding effect of scleral buckle, leading to unilateral choroidal effusion.
Joshi et al. (Thu,) studied this question.