Coronary angioscopy neointimal coverage grade corresponded significantly with neointimal thickness assessed by OCT (133, 215, and 305 μm for grades 1, 2, and 3, respectively; P<0.001).
Observational (n=161)
Does qualitative grading of neointimal coverage by coronary angioscopy correspond to quantitative measurements by optical coherence tomography after drug-eluting stent implantation?
Coronary angioscopy grading of neointimal coverage correlates well with high-resolution OCT measurements of neointimal thickness after DES implantation.
valor p: p=< 0.001
Abstract Objectives Coronary angioscopy (CAS) is a useful tool for estimating the neointimal coverage (NC) of stent struts, by showing the coverage grade. However, the neointimal coverage grade obtained with CAS has been qualitative, and it might be slightly less objective. Optical coherence tomography (OCT), which can provide high-resolution images, has enable to evaluate neointimal thickness covering stent in detail. The aim of this study is to compare neointimal proliferation between assessed by both coronary angioscopy and optical coherence tomography (OCT). Methods A total of 161 Drug-eluting stents were analyzed after implantation in chronic phase. We evaluated the grade of neointimal coverage (NIC) using 4 categories with angioscopy (0: no-coverage to 3: full-coverage). The neointimal area and thickness were also evaluated with OCT. Each stent was analyzed every 1mm along the longitudinal axis (1752 cross sections). Results The neointimal proliferation assessed by OCT was increased with increasing NIC grade of angioscopy (P 0.001). The NIC grade assessed by angioscopy was correspond to neointimal thickness as well as neointimal area assessed by OCT; NIC grade 1, 2, and 3 for neointimal thickness 133 ± 105, 215 ± 170, and 305 ± 187 μm, respectively (Figure 1). Conclusion The neointimal proliferation after DES implantation showed good correspondence between using by angioscopy and OCT.Figure1.Imaging findings Figure2.Representative cases
Sakai et al. (Sat,) conducted a observational in Drug-eluting stent implantation (n=161). Coronary angioscopy (CAS) vs. Optical coherence tomography (OCT) was evaluated on Neointimal proliferation (thickness and area) (p=< 0.001). Coronary angioscopy neointimal coverage grade corresponded significantly with neointimal thickness assessed by OCT (133, 215, and 305 μm for grades 1, 2, and 3, respectively; P<0.001).