What does this research mean for the field?

The hub-and-spoke strategy for NSTEMI patients is safe and efficient, with similar low complication rates compared to the single-center approach. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

This research aims to evaluate the efficacy and safety of a hub-and-spoke strategy for NSTEMI patients compared to traditional single-center treatment.

February 8, 2026

Efficacy and safety of an hub and spoke circuit for NSTEMI patients in italy

Resultado clave

The hub-and-spoke strategy for NSTEMI patients showed similar low rates of mortality and complications compared to single-center care in 1702 patients.

Puntos clave

This research aims to evaluate the efficacy and safety of a hub-and-spoke strategy for NSTEMI patients compared to traditional single-center treatment.
Conducted a retrospective multicenter cohort study in Italy.
Included 1702 NSTEMI patients from 2020 to 2024.
Compared outcomes between patients receiving hub-and-spoke care and those in single-center treatment.
In the hub-and-spoke group, there was one in-hospital death not related to the transport.
Two deaths occurred in the single hospital group.
Complications such as mechanical circulatory support and acute kidney injury were similarly low in both groups.

PICO estructurado

Does a hub-and-spoke strategy improve or maintain safety and efficacy compared to a single-center approach in patients with NSTEMI?

Población

1,702 patients with NSTEMI in Italy from 2020 to 2024, predominantly male.

Intervención

Hub-and-spoke strategy (transfer from peripheral hospital to central Hub center for angiographic evaluation and potential PCI, followed by same-day return to the hospital of origin)

Comparador

Single-center in-hospital strategy

Resultado

All-cause in-hospital mortality, need for mechanical circulatory support (Impella or IABP), acute definite stent thrombosis, major bleeding, acute kidney injury, and major access site vascular complications during the hospitalizationhard clinical

A hub-and-spoke transfer strategy for NSTEMI patients is safe and efficient compared to a single-center approach, with no significant differences in in-hospital mortality or complications.

Resultado numérico

Tasa de eventos absoluta: 0% vs 0%

Resumen

Abstract Background The "hub-and-spoke" (H 0.05). Conclusions The hub-and-spoke circuit represents an efficient and safe method for revascularization in patients with NSTEMI, saving time and resources in order to provide a complete revascularization.

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