Coronary computed tomography angiography (CCTA) led to a higher MACE rate in male patients at 5.3% compared to 1.9% in female patients.
Cohort (n=1,050)
No
Are there sex differences in coronary artery plaque composition and the prognostic value of high-risk plaque features for MACE in patients with suspected CAD?
Although men have a higher overall plaque burden and MACE rate, women exhibit a higher proportion of non-calcified plaques and a stronger association between high-risk plaque features and adverse events, emphasizing the need for sex-specific risk stratification.
Estimación del efecto: RR 2.79 (95% CI 1.42-5.50)
Tasa de eventos absoluta: 5.3% vs 1.9%
valor p: p=0.005
Based on a higher relative risk for women with high-risk plaque features, the findings of our study support the increased importance of a differentiated qualitative plaque analysis to improve the risk stratification for both sexes.
Plank et al. (Fri,) conducted a cohort in Coronary artery disease (n=1,050). Coronary computed tomography angiography (CCTA) vs. No intervention was evaluated on Major adverse cardiac event (MACE) (RR 2.79, 95% CI 1.42-5.50, p=0.005). Coronary computed tomography angiography (CCTA) led to a higher MACE rate in male patients at 5.3% compared to 1.9% in female patients.
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