Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.1996 · 1,402 citations
2. 2Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.1994 · 438 citations
3. 3Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor.1992 · 172 citations
4. 4Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease.1993 · 434 citations
5. 5Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene.1999 · 314 citations