Sevoflurane multiple Wash In/Wash Out at the end of anesthesia to reduce agitation: a multicenter double-blind randomized controlled trial (OPERA) | Synapse
February 19, 2026Open Access
Sevoflurane multiple Wash In/Wash Out at the end of anesthesia to reduce agitation: a multicenter double-blind randomized controlled trial (OPERA)
Puntos clave
The aim is to evaluate the effectiveness of sevoflurane wash in/wash out in reducing agitation at the end of anesthesia.
Conducted as a multicenter double-blind randomized controlled trial.
Participants received sevoflurane wash in/wash out at the end of anesthesia.
Agitation levels were measured post-anesthesia.
The intervention group experienced significantly lower agitation levels compared to the control group.
The findings indicate that sevoflurane wash in/wash out effectively reduces post-anesthetic agitation.
Resumen
ClinicalTrials.gov NCT04765488. Registered 15 February 2021.