What question did this study set out to answer?

To report rare complications associated with endovascular retrial and identify pathological findings.

February 22, 2026

Complications of endovascular MCA clot retrieval: hydrophilic polymer brain embolisation, localised MCA angiitis and recurrent ischaemic strokes

Puntos clave

To report rare complications associated with endovascular retrial and identify pathological findings.
Case report of a 72-year-old male
Endovascular clot retrieval followed by angioplasty on right MCA stroke
Postmortem examination to assess complications
Patient experienced recurrent ischaemic strokes four months post procedure
Postmortem revealed multiple bilateral infarcts and atherosclerosis
Foreign body-type giant cells found in M2 MCA with necrosis

Resumen

Reported cases of hydrophilic polymer embolisation (HPE) to the brain secondary to neurovascular procedures are rare. 1 A 72-year-old male presented with right MCA stroke, managed successfully with endovascular clot retrieval and angioplasty at M2. The patient represented four months later with recurrent right-sided ischaemic stroke followed rapidly by multiple successive ischaemic strokes. Postmortem examination revealed multiple bilateral infarcts and atherosclerosis of the cerebral and basilar arteries. There were foreign body-type giant cells associated with weakly polarisable and non-birefringent basophilic material in the right hemisphere capillaries. The right M2 MCA contained multinucleated foreign body-type giant cells on the luminal surface with patchy subluminal necrosis and sparse mural T-lymphocytes. There was background myointimal hyperplasia and duplication of the elastic lamina.

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