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Skin sensitization and systemic quantitative risk assessment of nickel in tattoo ink. | Synapse

February 27, 2026

Skin sensitization and systemic quantitative risk assessment of nickel in tattoo ink.

Puntos clave

To evaluate the risk of skin sensitization and systemic toxicity associated with nickel in tattoo ink.
Conducted a risk assessment to evaluate sensitization potential of nickel in tattoo ink
Analyzed existing data on nickel toxicity and exposure levels in tattoo applications
Skin sensitization from nickel in tattoo ink is unlikely based on current evidence
No expected non-cancer systemic toxicity from exposure to nickel in tattoo ink

Resumen

Skin sensitization and non-cancer systemic toxicity are not expected from exposure to Ni in tattoo ink.

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Cite This Study

Evans et al. (Tue,) studied this question.

synapsesocial.com/papers/69a1351ded1d949a99abec02 https://doi.org/https://doi.org/10.1080/15569527.2026.2626684

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1Pigments in American tattoo inks and their propensity to elicit allergic contact dermatitis2019 · 36 citations
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4Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients2007 · 327 citations
5Macrophage‐like rapid uptake and toxicity of tattoo ink in human monocytes2023 · 10 citations