What question did this study set out to answer?

To examine trends in HIV-1 subtype diversity among individuals tested between 2000 and 2019.

February 27, 2026

HIV-1 subtype diversity trends in a Northern California cohort

Puntos clave

To examine trends in HIV-1 subtype diversity among individuals tested between 2000 and 2019.
Analyzed HIV-1 resistance testing data from the Stanford Healthcare Clinical Virology Laboratory
Included samples from 9199 individuals in Northern California
Identified subtype distribution and changes over time
Non-B subtype viruses represented 3.5% of total cases, predominantly CRF01_AE (1.0%) and subtype C (1.0%)
Significant increase in CRF01_AE and CRF02_AG over the study period
Subtype B remained the most common, highlighting a growing diversity in the U.S. epidemic

Resumen

Between 2000 and 2019, the Stanford Healthcare Clinical Virology Laboratory performed HIV-1 resistance testing for 9199 individuals in Northern California. Nonsubtype B viruses were identified in 3. 5%, most often CRF01AE (1. 0%), subtype C (1. 0%), CRF02AG (0. 46%), and subtype A (0. 45%). Non-B viruses, particularly CRF01AE and CRF02AG, increased significantly over time. Although subtype B remained dominant, the rising presence of non-B subtypes reflects growing viral diversity within the U. S. epidemic.

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Cite This Study

Tao et al. (Wed,) studied this question.

synapsesocial.com/papers/69a1353eed1d949a99abeefa https://doi.org/https://doi.org/10.1097/qad.0000000000004399

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