What does this research mean for the field?

Maternal probiotic supplementation does not have a lasting effect on Th22 cell populations in infants, which may not be the main reason for preventing atopic dermatitis. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The study aims to investigate the impact of maternal probiotic supplementation on T-cell populations in infants and its relation to atopic dermatitis prevention.

March 1, 2026

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T-Cell Populations in Infancy After Maternal Probiotic Supplementation to Prevent Atopic Dermatitis.

DZDinastry Pramadita ZakiudinNorwegian University of Science and Technology ARAnne Dorthea Bjerkenes RøNorwegian University of Science and Technology VVVibeke VidemNorwegian University of Science and Technology

Puntos clave

The study aims to investigate the impact of maternal probiotic supplementation on T-cell populations in infants and its relation to atopic dermatitis prevention.
Observed T-cell populations in infants at 3 months after maternal probiotic supplementation.
Focused on the percentage of Th22 cells between probiotics and control groups.
Reduced percentage of Th22 cells in the probiotics group at 3 months.
Effect did not appear earlier or persist, suggesting limited role in preventing atopic dermatitis.

Resumen

We previously observed reduced Th22 percentage in the probiotics group at 3 months. However, since the effect was not seen earlier and did not last, it may not be the main reason for AD prevention.

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T-Cell Populations in Infancy After Maternal Probiotic Supplementation to Prevent Atopic Dermatitis.

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