What question did this study set out to answer?

This research aims to compare the fractal and geometric characteristics of iris nevi and cutaneous nevi through defined metrics.

March 2, 2026Open Access

Fractal Complexity and Pigment Architecture of the Human Iris: A Comparative Analysis Using Box-Counting Dimension and Nevi Characterization

Puntos clave

This research aims to compare the fractal and geometric characteristics of iris nevi and cutaneous nevi through defined metrics.
Formal pre-registration of the hypothesis
Calculation of Δ_D and Δ_A metrics
Prediction of cross-tissue correlations in a cohort of at least 40 subjects
Theoretical formulation without empirical data
Predicted positive correlation for box-counting dimension between iris and skin
Predicted positive correlation for Auric Index between iris and skin
Statistical significance indicated by p-values below 0.05

Resumen

Formal pre-registration of the hypothesis that pigmented biological structures across different tissues (iris nevi and cutaneous nevi) share measurable fractal and geometric organization principles. Defines two candidate metrics: - ΔD: cross-tissue fractal correlation index (box-counting dimension) - ΔA: cross-tissue golden proximity index (Auric Index extension) Predicts corr (Dᵢris, Dₛkin) > 0 and corr (Aᵢris, Aₛkin) > 0 across cohort n ≥ 40, p < 0. 05. No code. Theoretical formulation only. Pre-registered to establish priority and date of formulation. Related records: - Iris pipeline v5. 1: https: //doi. org/10. 5281/zenodo. 18806604- Iris preprint: https: //doi. org/10. 5281/zenodo. 18781344- Phyllotaxis base: https: //doi. org/10. 5281/zenodo. 18760369 --- v3: Added UBIRIS v1 external validation results (6 subjects, DOI 10. 5281/zenodo. 18818697). Section 5. 7 updated with first Auric Index signal in unknown population subject (UBIRIS 174, A=0. 400, p=0. 979). References 16-17 added.

Leer artículo completoexternamente

Me gusta

Guardar

Ver artículo completo