Sinusoidal cell-derived scores capture biologically relevant pathways of CLD progression and regression and can be measured from existing biopsy material available in most centers worldwide. Despite their retrospective derivation, these scores hold strong promise for prospective validation and clinical implementation as tools for patient stratification, monitoring, and therapeutic guidance.
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Sergi Guixé-Muntet
Hospital Clínic de Barcelona
Anabel Fernández-Iglesias
Hospital Clínic de Barcelona
David Fernando Lemus López
Gilead Sciences (United States)
BMC Medicine
University of Bern
University Hospital of Bern
Hospital Clínic de Barcelona
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Guixé-Muntet et al. (Sat,) studied this question.
synapsesocial.com/papers/69a67dd6f353c071a6f09cea — DOI: https://doi.org/10.1186/s12916-026-04733-y