Assessment of LDL receptor-dependent lipid lowering therapies in patients with homozygous familial hypercholesterolemia according to functional genotype

Puntos clave

• LDL receptor-dependent therapies effectively lower lipid levels in patients.
• Cholesterol levels decreased markedly, with specific attention to genotype functionality.
• Observational analysis focused on patients with homozygous familial hypercholesterolemia and their genotypes.
• These results highlight the importance of functional genotype in therapy responsiveness.