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Variation in gluteofemoral adipogenesis and the phenotype of adolescent PCOS | Synapse
March 3, 2026
Variation in gluteofemoral adipogenesis and the phenotype of adolescent PCOS
FZ
Francis de Zegher
LI
Lourdes Ibáñez
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
Puntos clave
Adolescents with polycystic ovary syndrome show significant variation in gluteofemoral adipogenesis, highlighting metabolic differences.
The study identifies specific adipocyte differentiation pathways related to hormonal imbalances associated with PCOS in teenage girls.
Assessment of metabolic syndrome markers reveals the importance of gluteofemoral fat in understanding PCOS phenotypes among adolescents.
Findings may indicate the need for targeted interventions in managing PCOS symptoms through diet and lifestyle adjustments.
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Zegher et al. (Sun,) studied this question.
synapsesocial.com/papers/69a759e3c6e9836116a1f488
https://doi.org/https://doi.org/10.1016/j.jacl.2025.10.061
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