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Metagenomic next-generation sequencing for the diagnosis and evaluation of pediatric pleural effusion: a case series | Synapse
March 3, 2026
Open Access
Metagenomic next-generation sequencing for the diagnosis and evaluation of pediatric pleural effusion: a case series
ZX
Zhufei Xu
Children's Hospital of Zhejiang University
LG
Lichao Gao
ZC
ZM Chen
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Puntos clave
Diagnosis of pediatric pleural effusion significantly improves using metagenomic next-generation sequencing, enabling better assessment of conditions.
The series indicates that metagenomic analysis might uncover diverse microbial profiles in pleural effusions, aiding treatment decisions.
Observational analysis of cases shows how effectively this method identifies pathogens and associated complications in children with pleural effusion.
Findings suggest that this diagnostic advancement may enhance clinical outcomes, with further validation needed to generalize across populations.
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Xu et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75a34c6e9836116a1fc7c
https://doi.org/https://doi.org/10.1186/s12890-026-04117-1
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