High incidence of intrahepatic cholangiocarcinoma in end-stage renal disease patients in Taiwan: analysis of a nationwide database with molecular insight of aristolochic acid exposure

Puntos clave

• Intrahepatic cholangiocarcinoma occurs more frequently in end-stage renal disease patients in Taiwan.
• The analysis indicates that exposure to aristolochic acid may contribute to this increased risk.
• Nationwide database investigation helps inform the molecular insights related to this cancer.
• Findings highlight a potential environmental risk factor for cholangiocarcinoma among renal patients.