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Diagnostic pitfalls of ESA-resistant anemia due to functional copper deficiency in a dialysis patient: a myelodysplastic syndrome mimic | Synapse
March 3, 2026
Open Access
Diagnostic pitfalls of ESA-resistant anemia due to functional copper deficiency in a dialysis patient: a myelodysplastic syndrome mimic
YI
Yukinobu Ikegishi
RA
Rokuo Abe
AM
Akiko Maehata
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Puntos clave
ESA-resistant anemia occurs frequently in patients with functional copper deficiency, complicating diagnosis.
Copper deficiency can mimic myelodysplastic syndrome, leading to misdiagnosis in some cases.
Diagnosis requires careful assessment of biomarkers and patient history, particularly for those on dialysis.
Highlighting the need for enhanced awareness around copper deficiency among clinicians is crucial for optimal care.
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Cite This Study
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Ikegishi et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a57c6e9836116a200dc
https://doi.org/https://doi.org/10.1007/s13730-025-01042-w