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AAVLINK: A potent DNA-recombination method for large cargo delivery in gene therapy | Synapse
March 3, 2026
AAVLINK: A potent DNA-recombination method for large cargo delivery in gene therapy
JL
Jianbang Lin
YL
Yunping Lin
Shenzhen Institutes of Advanced Technology
NL
Nana Liu
Peking University
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Puntos clave
This method improves gene therapy delivery by utilizing a potent DNA-recombination technique.
Key evidence indicates AAVLINK facilitates large cargo delivery, enhancing therapeutic potential.
Assessment using AAVLINK shows significant advancements in carrying larger gene constructs effectively.
The findings highlight the necessity for further validation in varied biological contexts.
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Lin et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a58c6e9836116a200e8
https://doi.org/https://doi.org/10.1016/j.cell.2025.12.039