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OCTN2-targeted and ROS-responsive hybrid polymeric micelles for oral delivery of docetaxel | Synapse
March 3, 2026
Open Access
OCTN2-targeted and ROS-responsive hybrid polymeric micelles for oral delivery of docetaxel
HS
Haihan Sun
JG
Jingxin Gou
XB
Xiaoshuang Bi
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Puntos clave
Hybrid polymeric micelles successfully deliver docetaxel, enhancing treatment efficacy.
Micelles demonstrate significant targeting efficiency to OCTN2, crucial for drug uptake.
The formulation involves optimizing ROS responsiveness to improve drug release in response to cellular stress.
Potential implications include improved cancer treatment strategies, indicated by enhanced bioavailability.
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Sun et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a67c6e9836116a20290
https://doi.org/https://doi.org/10.1186/s12951-026-04067-0