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Patient-derived lung organoids from bronchoalveolar lavage capture epithelial heterogeneity and disease biology in bronchopulmonary dysplasia | Synapse
March 3, 2026
Open Access
Patient-derived lung organoids from bronchoalveolar lavage capture epithelial heterogeneity and disease biology in bronchopulmonary dysplasia
SS
Shilpa Sonti
AC
Abiud Cantu
MG
Manuel Cantu Guttierez
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Puntos clave
Capturing epithelial heterogeneity, patient-derived lung organoids provide insights into bronchopulmonary dysplasia.
The analysis demonstrates the potential of bronchoalveolar lavage samples to inform on disease biology and pathology.
Using lung organoids, the study reveals distinct cellular responses associated with bronchopulmonary dysplasia.
This work highlights the need for deeper exploration of organoid technology in understanding complex lung diseases.
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Sonti et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a6dc6e9836116a2034f
https://doi.org/https://doi.org/10.1016/j.redox.2026.104057