These findings underscore the extract's dual mechanisms of action - antioxidant protection and insulin secretion enhancement - likely driven by flavonoids. The robust hypoglycemic response and pancreatic tissue protection provided by C. bonduc leaf extracts highlight their potential as valuable adjuncts in diabetes therapy. Further clinical evaluations and mechanistic studies are necessary to substantiate their clinical applicability.
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Febriza et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75a98c6e9836116a209e2 — DOI: https://doi.org/10.5114/pedm.2025.158548
Ami Febriza
Anisah Zahrah
Muhammadiyah University of Makassar
Nurul Andini
Hasanuddin University
SHILAP Revista de lepidopterología
Pediatric Endocrinology Diabetes and Metabolism
Hasanuddin University
Muhammadiyah University of Makassar
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