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Ether lipids influence cancer cell fate by modulating iron uptake | Synapse
March 3, 2026
Open Access
Ether lipids influence cancer cell fate by modulating iron uptake
RM
Ryan P. Mansell
IIT@MIT
SM
Sebastian Müller
Centre National de la Recherche Scientifique
JY
Jia-Shu Yang
Brigham and Women's Hospital
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Puntos clave
Ether lipids play a significant role in determining cancer cell fate by affecting iron uptake and metabolism.
The study identifies specific molecular pathways influenced by ether lipids that are critical in cancer progression.
Evaluation of cancer cell lines demonstrated that modulation of iron uptake leads to altered growth patterns and survival.
Further exploration of this mechanism may lead to innovative treatment strategies targeting iron metabolism in cancers.
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Cite This Study
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Mansell et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75aa3c6e9836116a20b82
https://doi.org/https://doi.org/10.1038/s41467-026-68547-5