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March 3, 2026
Erianin induces ferroptosis in ovarian cancer cells by upregulating PDP2 and activating the JNK signaling pathway
CF
Chaoyan Fan
MP
Min Peng
WZ
Wuguang Zhang
Puntos clave
Erianin induces ferroptosis in ovarian cancer cells, promoting cell death and reducing proliferation.
Cell viability decreased by over 50% after treatment with erianin in vitro within 24 hours.
Functional assays demonstrate activation of the JNK signaling pathway through PDP2 upregulation.
These findings highlight the potential of erianin as a novel therapeutic agent in overcoming ovarian cancer.
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Cite This Study
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Fan et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75ab8c6e9836116a20e85
https://doi.org/https://doi.org/10.1016/j.bbrc.2026.153353
Erianin induce ferroptosis en células de cáncer de ovario al regular al alza PDP2 y activar la vía de señalización JNK | Synapse