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The evolving role of ctDNA in colorectal cancer: guidance of adjuvant therapy or surveillance strategies? | Synapse
March 3, 2026
Open Access
The evolving role of ctDNA in colorectal cancer: guidance of adjuvant therapy or surveillance strategies?
LB
Laura G. Barrett
Cedars-Sinai Medical Center
AG
Alexandra Gangi
Cedars-Sinai Medical Center
AH
Andrew Hendifar
Cedars-Sinai Medical Center
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Puntos clave
ctDNA may effectively guide adjuvant therapy decisions in patients with colorectal cancer, especially postoperative.
In a recent observational analysis, ctDNA detection showed significant clinical utility for treatment monitoring and relapse identification.
Monitoring ctDNA levels can enhance current surveillance strategies, allowing for timely interventions and personalized care.
Findings suggest ctDNA testing could lead to improved outcomes, though further validation is required across diverse populations.
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Barrett et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75ac8c6e9836116a210cb
https://doi.org/https://doi.org/10.21037/tgh-25-75
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