Abstract This theoretical manuscript develops a domain-agnostic, non-biological, non-empirical framework for analyzing recurring organizational patterns observed across distinct phenomena: cancer-like cellular autonomy, postmortem transcriptional persistence, programmed senescence in Pacific salmon, vegetative states, parasitic behavioral hijacking (“zombie” hosts), epileptic automatisms, somnambulism, decerebrate locomotor organization, cryptobiosis/hibernation as reversible lowactivity regimes, insect survival after loss of central control (e. g. , headless cockroach), and fragmented organisms capable of regeneration (e. g. , planarian fragments). Departing from mechanistic comparison, we introduce a formal state-space defined by five universal dimensions: Integration (I), Module Autonomy (A), Goal Coherence (C), Behavioral Organization (O), and Reversibility (R). Within this space, we define attractor regions, trajectories, transition criteria, thresholds, and a metric criterion for structural equivalence across phenomena with different substrates and time scales. We then map the NOAH6 conceptual system (R0–R5, Sbad, Pₛtate) onto this abstract framework, expressing NOAH6 as a specific instance of state-space dynamics in hierarchically regulated systems rather than a domain-bound biomedical narrative. The result is a strictly structural language for comparing systemic degradation patterns across domains without invoking causation, physiology, or molecular mechanism.
Zakir Causevic (Mon,) studied this question.