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Trimethyltin chloride (TMT) - induced vascular injury through ubiquitination proteasome pathway - regulated GPX4 degradation | Synapse
March 3, 2026
Trimethyltin chloride (TMT) - induced vascular injury through ubiquitination proteasome pathway - regulated GPX4 degradation
YS
Yan Song
MC
Mi Chen
CW
Chen Wu
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Puntos clave
Vascular injury results from trimethyltin chloride exposure, affecting cellular health.
GPX4 degradation, linked to this injury, shows a significant pattern through the ubiquitination pathway.
The study utilized assays to investigate molecular changes related to ubiquitination and proteasome activity.
Findings suggest potential targets for therapeutic intervention in vascular damage due to toxic substances.
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Song et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b11c6e9836116a21b65
https://doi.org/https://doi.org/10.1016/j.intimp.2026.116250