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Astroglia and depression: A Gliocentric perspective from rodent models to therapeutic insights | Synapse
March 3, 2026
Astroglia and depression: A Gliocentric perspective from rodent models to therapeutic insights
RS
Rhea Subba
SE
Surendar Ellappan
SB
Sugato Banerjee
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Puntos clave
Astroglia play a crucial role in regulating neurotransmitters, affecting depression outcomes.
Key evidence shows that alterations in astroglia can impact emotion-related behaviors in rodents.
Analysis involves examining rodent models of depression and their glial cell activity over time.
These insights highlight the need for further exploration into astroglia-targeted therapies for depression.
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Subba et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b21c6e9836116a21e4e
https://doi.org/https://doi.org/10.1016/j.pnpbp.2026.111627