Design-led synthesis and multidimensional evaluation of novel thiadiazoles as multitarget anti-Alzheimer agents: kinetics, DFT and in silico mapping | Synapse
March 3, 2026
Design-led synthesis and multidimensional evaluation of novel thiadiazoles as multitarget anti-Alzheimer agents: kinetics, DFT and in silico mapping
Puntos clave
Thiadiazoles exhibit significant potential as multitarget anti-Alzheimer agents, addressing various disease mechanisms.
In kinetic evaluations, new compounds displayed improved inhibition rates compared to existing therapies.
Analysis using density functional theory (DFT) provided critical insights into molecular behavior and interactions.
This research highlights promising targets for future drug development, suggesting a multifaceted approach to Alzheimer's treatment.