CiLSM14Aa acts as a cytosolic dsRNA sensor to activate antiviral immunity against GCRV-II

Puntos clave

• Antiviral immunity is activated by the cytosolic dsRNA sensor CiLSM14Aa, linking to GCRV-II resistance.
• Key metric shows that activation of immunity significantly reduces viral replication rates during infection.
• Observational analysis conducted on immune responses in cells exposed to GCRV-II and CiLSM14Aa sensor activation.
• This study highlights the potential for developing targeted therapies based on CiLSM14Aa's sensitivity to viral dsRNA.