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March 3, 2026
TDCIPP disrupts decidual macrophage function to induce miscarriage through ferroptosis-mediated DNA damage
YZ
Yongbo Zhao
Obstetrics and Gynecology Hospital of Fudan University
YZ
Yongbo Zhao
Obstetrics and Gynecology Hospital of Fudan University
JS
Jiani Sun
Shanghai First Maternity and Infant Hospital
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Puntos clave
Miscarriage is induced by TDCIPP-mediated disruption of decidual macrophage function, leading to ferroptosis.
Key evidence indicates that DNA damage associated with ferroptosis is significantly elevated after TDCIPP exposure.
Analysis of macrophage function demonstrates how TDCIPP disrupts normal physiological processes in the decidua and induces miscarriage.
Highlights the potential environmental impact of TDCIPP exposure on reproductive health and necessitates further investigation.
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TDCIPP disrupts decidual macrophage function to induce miscarriage through ferroptosis-mediated DNA damage | Synapse
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Zhao et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b7ec6e9836116a22e47
https://doi.org/https://doi.org/10.1016/j.jhazmat.2026.141271