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Claudin 18.2 expression in gastroesophageal adenocarcinoma: biomarker overlap and association with clinical outcomes in a European cohort | Synapse
March 3, 2026
Open Access
Claudin 18.2 expression in gastroesophageal adenocarcinoma: biomarker overlap and association with clinical outcomes in a European cohort
ET
E. Terán
Hebron University
RP
R. Pazo
Hospital Universitario Miguel Servet
LC
L. Caritá
Vall d'Hebron Institut de Recerca
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Puntos clave
Claudin 18.2 expression correlates with clinical outcomes in gastroesophageal adenocarcinoma, indicating its potential as a prognostic biomarker.
The study highlights a substantial overlap of claudin 18.2 with other established biomarkers in this cancer type, underlining its importance.
Observational analysis across a European cohort demonstrates the association between claudin 18.2 levels and patient prognosis.
These findings support the exploration of new treatment options targeting claudin 18.2, potentially enhancing patient management strategies.
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Terán et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b88c6e9836116a22f81
https://doi.org/https://doi.org/10.1016/j.esmoop.2025.106053
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