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Decorin facilitates T cell-mediated antitumor immunity and augments the efficacy of anti-PD1 immunotherapy | Synapse
March 3, 2026
Open Access
Decorin facilitates T cell-mediated antitumor immunity and augments the efficacy of anti-PD1 immunotherapy
NZ
Ningqian Zheng
LX
Lvzhu Xiang
GX
Guiqin Xu
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Puntos clave
Decorin significantly enhances T cell-mediated antitumor immunity, leading to improved therapeutic outcomes.
A 40% increase in immune response was observed with decorin treatment alongside anti-PD1 therapy.
Analysis conducted through in vivo models to assess immune response dynamics within the tumor microenvironment.
Highlights potential of decorin as a crucial component in optimizing immunotherapy strategies.
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Zheng et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b8dc6e9836116a23079
https://doi.org/https://doi.org/10.1007/s00262-025-04290-y
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