Evaluating the implications of K-Ras, KEAP1/NRF2-mediated signaling pathways and metabolic alterations in urethane-induced lung cancer

Puntos clave

• Urethane exposure induces alterations in K-Ras signaling pathways, contributing to lung cancer.
• Key findings indicate a significant role of KEAP1/NRF2-mediated regulation in cancer progression.
• Observational analysis details metabolic alterations linked to K-Ras and NRF2 pathways in lung tissue.
• Highlights the potential for therapeutic targets within metabolic pathways related to lung cancer.