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Demonstration of the protective effects of melatonin and naringenin against hepatic injury induced by bile duct ligation in male rats | Synapse
March 3, 2026
Demonstration of the protective effects of melatonin and naringenin against hepatic injury induced by bile duct ligation in male rats
MA
Majid Asadi‐Shekaari
Kerman University of Medical Sciences
GO
Ghasem Oveis
Mazandaran University of Medical Sciences
MM
Marzieh Maneshian
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Puntos clave
Hepatic injury is significantly reduced in male rats treated with melatonin and naringenin.
An observed decrease in biomarkers for oxidative stress indicates effective protection from liver damage.
Experimental model utilized was bile duct ligation in male rats to simulate hepatic injury.
Results suggest potential clinical applications for melatonin and naringenin in liver health and disease.
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Asadi‐Shekaari et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c19c6e9836116a24915
https://doi.org/https://doi.org/10.1007/s00580-026-03755-5